Seventh Annual Recombinant Protein Therapeutics
Hotel Del Coronado
1500 Orange Ave.
Coronado, California
Fusion Proteins & Beyond

This meeting addresses the innovative strategies and supporting technologies that spur progress, including engineering the Fc regions. Persistent challenges
will be discussed, along with case studies of recombinant protein therapeutic products. In addition, the meeting will explore the different classes of therapeutic
fusion proteins currently in development.

Schedule of Presentations:

Monday, January 10, 2011
07:30:00 Conference Registration | Morning Coffee
08:25:00 Innovating to Overcome Challenges
08:30:00 Chairperson’s Opening Remarks
08:45:00 Opening Keynote Presentation | Protein Therapeutics: Triumphs and Challenges Lynne Regan
09:35:00 Featured Presentation | Recombinant Proteins for Targeting Intracellular Compartments of Cancer Cells Waldemar Debinski
10:05:00 Coffee Break Featuring Emerging Companies/Products
10:35:00 Case Studies
10:45:00 ACE2: From Concept to the Patient Manfred Schuster
11:15:00 SEEDbody Fusion Proteins Alec W. Gross
11:45:00 Recombinant Factor IX Monomeric Fc Fusion Protein (rFIXFc) | Concept to Clinic Alan J. Bitonti
12:15:00 Close of Morning Session
12:30:00 Luncheon Presentations | or Lunch on Your Own
13:55:00 Optimizing Properties
14:00:00 Chairperson’s Remarks
14:05:00 Characterization of Disulfide Linkages of an Albumin Fusion Protein Andréa Meeler
14:35:00 In vitro Characterization of an Acetylcholine Receptor-Transferrin Fusion Protein Serene Josiah
15:05:00 Biopolymer ELP-Fusion Protein Technology Significantly Enhances the Pharmacology, Safety, and Efficacy of Biotherapeutics Lynne M. Georgopoulos
15:35:00 Sponsored Presentation
15:50:00 Refreshment Break | Featuring Emerging Companies/Products
16:25:00 Designing Fusion Proteins to Fight Disease
16:30:00 Recombinant Transferrin Fusion Proteins for the Activation of Protein Precursors in Liver: The Conversion of Proinsulin to Insulin as a Transferrin Fusion Protein in Hepatoma Cells Wei-Chiang Shen
17:00:00 Small and Simple Cysteine-Containing Fusion Tag for Site-Specific Payload Conjugation Joseph Backer
17:30:00 SCORPION™ Therapeutics | Multi-Specific Proteins with Enhanced Biologic Activity Kendall M. Mohler
18:00:00 Welcoming Reception | Exhibit Hall
19:30:00 Close of Day
Tuesday, January 11, 2011
07:30:00 Breakfast Presentation | Coffee
08:10:00 Engineering the Fc Regions
08:15:00 Chairperson’s Opening Remarks
08:20:00 Fc Fusion Peptide and Protein Biopharmaceuticals – Successes and Challenges Chichi Huang
08:50:00 Engineering and Characterization of LY 2189265, a Novel Long-Acting Glucagon- Like Peptide-1 (GLP-1)-Fc Fusion Protein Wolfgang Glaesner
09:20:00 Engineering Antibody-Cytokine Fusion Proteins (Immunocytokines) for Optimal Anti-Tumor Activity and Reduced Immunogenicity in Patients Stephen Gillies
09:50:00 Sponsored Presentation
10:05:00 Coffee Break | Exhibit and Poster Viewing
10:35:00 Engineering Inhibitors
10:45:00 Targeting Extended Protein Interactions Surfaces with Photo-Switchable Peptides Katja Arndt
11:15:00 Engineering Recombinant Targeted Secretion Inhibitors from Botulinum Neurotoxin John Chaddock
11:45:00 Optimization and Generation of Fusion Proteins for Therapeutic and Diagnostic Applications Christopher J. Scott
12:15:00 Close of Morning Session
12:30:00 Luncheon Presentations | or Lunch on Your Own
14:00:00 BuzZ Session A | Interactive participation leads to problem-solving solutions and future collaborations around focused topics.
14:45:00 Refreshment Break | Exhibit Viewing and Poster Awards
15:30:00 BuzZ Session B | Interactive participation leads to problem-solving solutions and future collaborations around focused topics.
16:15:00 End of Conference
16:20:00 Registration for Short Courses
16:30:00 Concurrent Dinner Short Courses
3D Tissue Models
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