Microbiota and Mucosal Immunology: The Interface in Health and Disease
Grand Hyatt San Francisco
345 Stockton Street San Francisco, CA 94108 USA
San Francisco, California

     *  Margaret McFall-Ngai (University of Wisconsin, USA )

     *  Richard Flavell (Yale University, USA )

     *  David Artis (University of Pennsylvania School of Medicine, USA )

     *  Yasmine Belkaid (National Institute of Allergy and Infectious
       Diseases, National Institutes of Health, USA )

     *  Jason Brenchley (National Institute of Allergy and Infectious
       Diseases, National Institutes of Health, USA )

     *  Andrea Cerutti (Mount Sinai School of Medicine, USA )

     *  Alexander Chervonsky (The University of Chicago, USA )

     *  Marco Colonna (Washington University School of Medicine, USA )

     *  Dusko Ehrlich (National Institute of Agronomic Research, France)

     *  Brett Finlay (The University of British Columbia, Canada)

     *  Larry Forney (University of Idaho, USA )

     *  Lora Hooper (University of Texas Southwestern Medical Center, USA

     *  Akiko Iwasaki (Yale University School of Medicine, USA )

     *  Andrew MacPherson (McMaster University, Canada / Bern University
       Hospital, Switzerland)

     *  Sarkis Mazmanian (California Institute of Technology, USA )

     *  Gabriel Nunez (University of Michigan, USA )

     *  Eric Pamer (Memorial Sloan-Kettering Cancer Center, USA )

     *  Dana Philpott (University of Toronto, Canada)

     *  Fiona Powrie (University of Oxford, UK)

     *  Phillippe Sansonetti ( INSERM U786, Institut Pasteur, France)

     *  Thaddeus Stappenbeck (Washington University, USA )

     *  Warren Strober (National Institute of Allergy and Infectious
       Diseases, National Institutes of Health, USA )

   Nature Immunology, Nature Reviews Microbiology and Mucosal Immunology

   Microbiota and mucosal immunology: the interface in health and disease

   Hosts and their microbiomes have evolved symbiotic relationships that
   establish and maintain homeostasis of the immune system at mucosal
   surfaces. This conference will bring together scientists and
   clinicians from various backgrounds to provide a comprehensive view of
   the interaction of the microbiome and the host immune responses at
   mucosal surfaces. In particular, the focus will be on the recent
   progress in understanding the composition and behavior of commensal
   microbiota, their ability to induce and become controlled by host
   innate and adaptive immunity, bacterial mechanisms to circumvent host
   immune responses and the pathological consequences of disrupting this
   finely tuned immunological balance.

   April 14-16, 2011
   Grand Hyatt San Francisco
   San Francisco, CA, USA

   Original photo by Edith Porter and Tomas Ganz. Art by Lewis Long.

   Brian Kelsall, Editor, Mucosal Immunology and National Institute for
   Allergy and Infectious Diseases
   Sarkis Mazmanian, California Institute of Technology
   Christiaan van Ooij, Chief Editor, Nature Reviews Microbiology
   Bali Pulendran, Emory University
   Jamie D.K. Wilson, Chief Editor, Nature Immunology

   Abstract submission and early registration deadline:

   February 21, 2011

   For more information and to register visit:

Schedule of Presentations:

Thursday, April 14, 2011
12:00:00 Conference Registration
14:00:00 Welcome and Introductions
14:15:00 Opening Keynote Lecture | Title TBD Margaret McFall-Ngai
15:10:00 Session 1 | Microorganisms of the mucosa | Behavior and dynamics
15:15:00 Antibiotics and mucosal innate immune defense against bacterial infection Eric Pamer
15:45:00 The intimate relations of vaginal bacteria and women Larry Forney
16:15:00 Coffee Break
16:45:00 Quantitative metagenomic analysis of the human intestinal microbiome reveals associations of bacterial species and chronic disease Dusko Ehrlich
17:15:00 Short talk
17:30:00 Host autophagy programs shape the mucosal microbial community Thaddeus Stappenbeck
18:00:00 Poster Session and Welcome Reception
Friday, April 15, 2011
08:15:00 Continental Breakfast
08:55:00 Session 2 | The host-commensal interface | Development, innate immunity and tolerance
09:00:00 Immunity to commensal bacteria at the intestinal epithelial surface Lora Hooper
09:30:00 Microbial colonization and immune cell homeostasis David Artis
10:00:00 Short talk
10:15:00 Coffee Break
10:45:00 Adaption of the mucosal immune system: insights from reversible intestinal colonisation Andrew MacPherson
11:15:00 Immune modulation by beneficial gut bacteria mediates health and disease Sarkis K. Mazmanian
11:45:00 Lunch
12:55:00 Session 3 | Microorganisms versus host | Pathogenic mechanisms
13:00:00 Symbionts and pathogens at mucosal surfaces | the yin and yang of innate immunity Philippe J Sansonetti
13:30:00 Innate and adaptive responses against commensals in the control of infections Yasmine Belkaid
14:00:00 Short talk
14:15:00 Microbial translocation and immune activation in progressive HIV/SIV infections Jason Brenchley
14:45:00 Interactions between the microbiome and enteric pathogens Brett B Finlay
15:15:00 Coffee Break
15:40:00 Session 4 | Microorganisms versus host | Host response
15:45:00 Regulation of human splenic marginal zone B cells by microbial signals Andrea Cerutti
16:15:00 Title TBD Fiona Powrie
16:45:00 NK cells in mucosal immunity Marco Colonna
17:15:00 Short talk
17:30:00 Regulation of mucosal immunity by Nod proteins Dana Philpott
18:00:00 Reception and Conference Dinner
Saturday, April 16, 2011
08:15:00 Continental Breakfast
08:55:00 Session 5 | Mucosal immunity in health and disease
09:00:00 Microbiota and autoimmunity Alexander Chervonsky
09:30:00 Control of enteric pathogens and intestinal immunity by Nod-like receptors Gabriel Nunez
10:00:00 Short talk
10:15:00 Coffee Break
10:45:00 Role of microbiota in mucosal immunity Akiko Iwasaki
11:15:00 Pathogen and commensal induction of NOD1 signaling Warren Strober
11:45:00 Lunch
12:45:00 Closing Keynote Lecture | The role of microbiota in chronic inflammatory disease Richard A. Flavell
13:45:00 Closing Remarks
14:00:00 Conference Closes
3D Tissue Models
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