Preclinical Development
The Moscone North Convention Center
747 Howard Street
San Francisco-94103, CA
Molecular diagnostics


Molecular Diagnostics
Mastering Medicinal Chemistry
Pathway Analysis
Stem Cells Congress
R&D Risk Mitigation
Clinical Trials Asia
Preclinical Development
Translational Medicine
Cytokine-Based Therapeutics
Cancer Molecular Markers
Trends in Drug Safety

Schedule of Presentations:

Tuesday, March 25, 2008
07:00:00 Registration Open
Wednesday, March 26, 2008
07:00:00 Registration Open
09:40:00 Grand Opening Refreshment Break in the Exhibit Hall
11:00:00 Chairperson’s Remarks William B. Mattes
11:10:00 Improving R&D Productivity Through Better Preclinical Decision Making and Science
11:55:00 Toxicity Testing in the 21st Century: Opportunities for Pharmaceutical Risk Assessment Daniel Krewski
12:00:00 New Presentation
12:40:00 Technology Spotlight (Sponsorship Available)
13:10:00 Walk & Talk Luncheon in the Exhibit Hall ADVANCES IN TOXICITY TESTING AND PREDICTION
14:15:00 Chairperson’s Remarks Joy A. Cavagnaro
14:20:00 Overview William B. Mattes
14:40:00 From Publication to Practice: Interlaboratory Validation of Microarray and QPCR-based Signatures for Predicting Carcinogenicity in the Rat Mark Fielden
15:00:00 Mechanistic Cardiac Modeling: Concepts and Utility in Drug Development Anna Georgieva
15:20:00 Advances in Liver Toxicity Testing: What’s on the Horizon? Holly L Jordan
15:40:00 SDAR: Spectrometric Data Activity Relationship Modeling Dan Buzatu
15:55:00 Modeling and Assaying Dioxin-Like Biological Effects for Both Dioxin-Like and Certain Non-Dioxin-Like Compounds Jon Wilkes
16:20:00 Reception in the Exhibit Hall (Sponsorship Available)
17:00:00 Break-out Discussions in the Exhibit Hall
18:00:00 End of Session
Thursday, March 27, 2008
08:25:00 Chairperson’s Remarks Judith K Marquis
08:30:00 Challenges of Doxercalciferol, a Prodrug of a Potent Vitamin D Hormone
09:00:00 Speaker to Be Determined
09:30:00 Managing QT Prolongation Judith K Marquis
10:00:00 Technology Spotlight Sponsored by Digital Toxicologic Pathology in Preclini- cal Contract Research: The Importance to Pharmaceutical and Biotech Partners Steven J Potts
10:30:00 Poster Competition & Refreshment Break in the Exhibit Hall
11:30:00 Discovery and Development of AMD3100 as a Stem Cell Mobilizer Ron T MacFarland
12:00:00 The Importance of Integrating the Disciplines to Increase the Probability Cindy Berman
12:30:00 Luncheon Workshop (Sponsorship Available) or Lunch on Your Own
13:30:00 Break
13:45:00 Chairperson’s Remarks Eric A Blomme
13:50:00 Integration of Novel Technologies in Discovery and Early Development Toxicology Development Toxicology Eric A Blomme
14:20:00 A Lead Optimization and Early Development Toxicology Strategy Specifi c to Novel Oncology Targets Carl L Alden
14:50:00 Predictive Value of in Vitro Safety Studies Willi Suter
15:20:00 Plenary Keynote Speaker Ice Bound - A Doctor’s Incredible Battle for Survival at the South Pole Jerri Nielsen
16:00:00 Ice Cream Refreshment Break in the Exhibit Hall with BEST OF SHOW AWARDS
16:45:00 Strategies for Early Toxicity Testing with Focus on Genotoxicity Evaluations Michael J Schlosser
17:15:00 Speaker to Be Determined
17:45:00 End of Session
Friday, March 28, 2008
08:30:00 Chairperson’s Remarks Mary Haak Frendscho
08:35:00 Defining and Finding Relevant Animal Models: The Evolution of “Relevant” During Development Nancy Wehner
09:05:00 Predicting Cardiac Toxicity with Adjuant Trastuzumab Therapy Ellie Guardino
09:35:00 Translating Safety from Animals to FIH Studies of Biologics Science or Art? Lauren E Black
10:05:00 Technology Spotlight (Sponsorship Available)
10:20:00 Coffee Break in the Foyer
11:00:00 Development of an in Vitro Cytokine Release Assay and its Predicative Value Jing Min
11:30:00 The Early Development of Raptiva® (efalizumab) for Plaque Psoriasis Kathrin R Meyers
12:00:00 Luncheon Workshop (Sponsorship Available) or Lunch on Your Own
13:00:00 Chairperson’s Remarks Kohkan Shamsi
13:05:00 Imaging Biomarkers in Early Clinical Development of Novel Therapeutic Agents Jeffrey Evelhoch
13:35:00 Imaging in Phase II/III Clinical Development Haren Rupani
14:05:00 Imaging as a Biomarker in Oncology Drug Trials and Improving Cancer Patient Care Gary J. Kelloff
14:35:00 The Promises and Realities of Imaging as a Translational Biomarker in Drug Development Tim Mccarthy
15:05:00 Close of Conference
3D Tissue Models
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