AsiaTIDES: Oligonucleotide and Peptide® Research, Technology and Product Development
Sheraton Miyako Hotel

Tokyo, Japan
AsiaTIDES: Oligonucleotide and Peptide® Research, Technology and Product Development
IBC Life Sciences
Sheraton Miyako Hotel

Schedule of Presentations:

Tuesday, February 26, 2013
04:40:00 Antisense Oligonucleotide Therapy for the Treatment of Neurodegenerative Diseases Frank Bennett
08:30:00 Registration and Coffee/Tea Mimoun Ayoub
09:00:00 Start of Tutorial René Thürmer
09:00:00 Principles of Oligonucleotide In Vivo Delivery Dmitry Samarsky
09:40:00 Local Delivery: Lessons Learned from 'Self-Delivering' RNAi Compounds
10:20:00 Networking Refreshment Break
10:50:00 Size Matters, Gymnosis - Breakthrough Design, Chemistries And Applications Troels Koch,
11:30:00 Lipid Nanoparticles for Oligonucleotide Delivery: From Basic Principles to the Clinic
12:00:00 Registration for Main Conference Begins
12:00:00 Chairman's Concluding Remarks and Discussion Dmitry Samarsky
12:30:00 Close of Tutorial
12:30:00 Close of Tutorial
13:30:00 Chairman's Remarks Bob D. Brown
13:40:00 Oligonucleotide Therapeutics: The Third Platform for Drug Development Arthur M. Krieg
14:20:00 Development of Lipid Nanoparticle (LNP) Based Delivery System of siRNA Targeting Extrahepatic Tumor
15:00:00 Networking Refreshment Break
15:20:00 Defying Difficult Diseases: Protease Inhibitors andthe Click Peptide Concept Using O-Acyl Isopeptides Yoshiaki Kiso
16:00:00 The Journey Together: Omontys (Peginesatide Injection) - From Bench to Bedside
17:30:00 Close of AsiaTIDES Day One Sessions
18:30:00 Networking Dinner
Wednesday, February 27, 2013
08:30:00 Registration and Coffee/Tea
08:55:00 Chairman's Remarks William S. Marshall,
09:00:00 microRNA Targeting for Cardiovascular Disease Intervention William S. Marshall,
09:30:00 Development of NF-kB Decoy ODN Coated PTA Balloon Catheter for Suppressing Restenosis of Blood Vessels
10:00:00 Challenges for Preclinical and Clinical Development of siRNA Therapeutics in China
10:30:00 Networking Refreshment Break in Poster and Exhibit Hall
11:15:00 Therapeutic Development Using Second Generation RNAi Triggers with Enhanced Cellular Delivery Dong-ki Lee
11:45:00 High Potency in vivo Gene Silencing Activity via Chemically-Modified siRNAs Xianbin Yang
12:15:00 Networking Luncheon in Poster and Exhibit Hall
13:30:00 Chairwoman's Remarks Pamela A. Pavco,
13:45:00 Update on RXI-109, an RNAi Compound in Clinical Development to Reduce Dermal Scarring Pamela A. Pavco
14:15:00 Dbait - New Approach in Cancer Therapy by Jamming DNA Repair Signaling to Overcome Tumor's Resistance to Conventional Cancer Therapies: From Concept to Clinic Jiang Shen Sun
14:45:00 Efficacy of Treating HBV Infection by Combining the Nucleic Acid Polymer REP 9AC' with Pegasys™ or Zadaxin™ Andrew Vaillant
15:15:00 Networking Refreshment Break in Poster and Exhibit Hall
16:00:00 Development of Liposomally Formulated siRNA for RNAi-Based Therapy: Atu027 for Therapeutic Application in Oncology Joerg Kaufmann
16:30:00 First Clinical Phase IIa Data of the Mirror-Image RNA Oligonucleotide NOX-A12 Sven Klussmann
17:00:00 Miravirsen Clinical Update - First MicroRNA Drug for Hepatitis C Henrik Ørum
17:30:00 Networking Reception in Exhibit and Poster Hall
Thursday, February 28, 2013
06:00:00 New Presentation
08:55:00 Co-Chairs' Remarks
09:00:00 cGMP Manufacturing of a Conjugated Oligonucleotide
09:25:00 Differential Scanning Calorimetry (DSC) as a Tool to Characterize Oligonucleotides in Solution Hüseyin Aygün
09:50:00 Presentation to be announced
10:15:00 A Rapid 2-D UHPLC UV/MS Method for Debottlenecking the Oligo Purification Process Paul Metz
10:40:00 Networking Refreshment Break in Poster and Exhibit Hall
11:15:00 The Use of Fmoc-Pseudoproline Dipeptides in the Synthesis of Large Peptides
11:45:00 Analytical Methods in Peptide Manufacturing: From Starting Materials to Drug Substances
12:15:00 Advantages of High Resolution Mass Spectrometry in Peptide Synthesis
12:45:00 Networking Luncheon in Poster and Exhibit Hall
13:55:00 Chairwoman's Remarks Kathryn L. Ackley
14:00:00 The Excaliard Story: From Start-up through Clinical Success and Acquisition by Pfizer Dirk Haussecker
15:10:00 Networking Refreshment Break in Exhibit and Poster Hall and Final Chance to See Exhibits and Posters
15:50:00 Co-Chairmans' Remarks Arthur A. Levin
16:00:00 OSWG and JPMA Joint Session: Topic for Consideration and Debate: Nonclinical Safety Assessment of Oligonucleotides (Provisional) Kazuchika Takagaki
16:30:00 Discussion and Debate on Nonclinical Safety Assessment
17:00:00 Clinical Experiences with Oligonucleotide Therapeutics and the Productivity of Animal Models for Human Responses Arthur A. Levin
17:30:00 Special Issues in Regulating Oligonucleotides and Peptides Regarding CMC René Thürmer
18:00:00 Close of AsiaTIDES
3D Tissue Models
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