Infectious Disease Genomics and Global Health
Wellcome Trust Conference Centre
Wellcome Trust Genome Campus
Hinxton, Cambridge, UK
The sixth Infectious Disease Genomics and Global Health conference will emphasize the application of genomic technologies to problems of infectious disease in a global health context. Infectious disease is a major burden on healthcare throughout the world, particularly in developing countries. Disease agents do not respect borders; therefore, an integrated global approach is necessary to understand transmission and evolution of infectious disease agents. Recent advances in genomic technologies are delivering new approaches to these problems, and these will be the major focus of the meeting. These technologies promote cross-fertilisation amongst previously disparate fields, and we therefore welcome abstracts covering any area in this field. 

Schedule of Presentations:

Wednesday, October 16, 2013
11:45:00 Registration and Lunch
12:40:00 Session 1: Population Genomics Olivo Miotto, Tulio de Oliveira
12:45:00 Developing genetic tools for surveillance of emerging drug resistance in P. falciparum Olivo Miotto
12:55:00 HIV & TB genomics for patient management, research and capacity building in Africa Tulio de Oliveira
13:15:00 Computational methods for identifying reassortment events under selection in th e evolution of human influenza A viruses
13:35:00 Multilocus sequence typing system (MLST) of E ntamoeba histolytica : evide nce of genetic diversity and a parasite genetic component to virulence
13:55:00 Complex patterns of host switching in new world arenaviruses
14:15:00 Inference of genome - wide evolutionary networks for influenza A viruses
14:35:00 Core genome allele - based typing clarifies epidemiology of nosocomial methicillin resistant Staphylococcus aureus clusters
15:25:00 Afternoon Tea
16:00:00 Session 2: Epidemiology and Publ ic Health
16:05:00 Clonal waves and genomic diversification: epidemiology of meningococcal disease in the African meningitis belt
16:30:00 HIV genome - wide diversity in la rge - scale patient populations
16:50:00 A whole - genome sequence assessment of outbreak - associated and predominant clones of Listeria monocytogenes
17:10:00 Genomic diversit y in candidate virulence - associated genes in clinical strains of ocular Chlamydia trachomatis from a trachoma - hyperendemic population on the Bijagós Archipelago of Guinea Bissau in West Africa
17:30:00 Whole genomic sequencing evidence for replacement of an established ESBL E. coli ST131 strain by an introduced strain in a nursing home.
17:30:00 The Lake Victoria island intervention study on worms and allergy - related diseases: can genetic under - pinnings of worm - allergy associations be explored?
18:10:00 Genomic epidemiology of tuberculosis: impl ications for global health Jennifer Gardy
18:40:00 Poster s ession with drinks reception
19:40:00 Dinner
Thursday, October 17, 2013
09:00:00 Session 3: Genomics of Bact erial Diseases Duccio Medini
09:05:00 The search for host genes influencing susceptibility to enteric infections
09:30:00 Using whole genome screens to investigate the virulence mechanisms in Citrob acter rodentium in vitro and in vivo
09:50:00 The serum resistome of a globally disseminated multidrug resistant uropathogenic Escherichia coli clone
10:10:00 Characterisation of fimbrial phenotypes & genotypes in UK Bordetella pertussis isolates by paired flow cytometry & whole genome sequencing of individual cultures
10:30:00 Morning Coffee
11:00:00 Session 3: Genomics of Bacterial Diseases continued:
11:05:00 Neisseria meningitidis is structured in clades associated with restriction modification systems that modulate homologous recombination Duccio Medini
11:30:00 Burkholderia pseudomallei su ppresses caenorhabditis elegans immunity by specifically targeting a GATA transcription factor
11:50:00 Methylome diversification through changes in the sequence specificity of DNA methyltransferases
12:10:00 Robust analysis of structural variations using paired - end sequencing data
12:40:00 Lunch
14:00:00 Session 4: Parasites and vectors Joanne P. Webster
14:05:00 Application of schistosome population genetics and genomics for elucidating disease dynamics and evaluating control. Joanne P. Webster
14:30:00 Genome and transcriptome of the zoonotic hookworm Ancylostoma ceylanic um
14:50:00 Identification of candidate genes associated with carbamate insecticide resistance in the lymphatic filariasis vector Culex quinquefasciatus
15:10:00 High - throughput characterization of P. vivax invasion antigen library
15:30:00 The mechanism of increased E. histolytica susceptibility due to the Q223R leptin receptor mutation
15:50:00 Generation of population genomics data for a parasite of nucleated host cells Joana Silva
16:20:00 Afternoon Tea
17:00:00 Keynote Lecture George Weinstock
17:10:00 Infectiou s Disease Elimination: Science Confronts Reality James W. Kazura
18:00:00 Poster s ession with drinks reception sponsored by Pacific Biosciences
19:00:00 Conference Dinner
19:05:00 Bar open
Friday, October 18, 2013
09:00:00 Session 5: Surveillance of Disease Dag Harmsen, Frank Aarestrup
09:05:00 Towards Standardized Bacterial Whole Genome Sequencing for Global Surveillance Dag Harmsen
09:30:00 Enhancing epidemiological surveillance of HIV with molecular data
09:50:00 Determining the threshold at which an enteric pathogen effects health
10:10:00 Routine genotyping of bovine tuberculosis by WGS
10:30:00 Morning Coffee
11:00:00 Session 5: Surveillance of Disease continued:
11:05:00 Global detection and control of pathogenic microorganisms using whole genome sequencing Frank Aarestrup
11:30:00 Distribution of HPV -16 variants by genetic ancestry in cervical cancer cases of Colombia
11:50:00 The MiSeq DNA sequencing platform and application in clinical microbiology
12:10:00 Lunch
13:30:00 Session 6: Microbiome Maria Gloria Dominguez-Bello, Phil Tarr
13:35:00 Genomics and Global Health in the context of transculturation Maria Gloria Dominguez-Bello
14:00:00 Diarrhea in young children from low-income countries leads to large-scale alterations in intestinal microbiota composition
14:20:00 16s rRNA analysis of tsetse fly microbiome
14:40:00 Gut Pathogens: Whole Bacterial Genome Sequencing and Infection Control Phil Tarr
15:10:00 Conference summary and closing remarks
15:30:00 Coaches Depart for Stansted and Heathrow airports
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