3D Tissue Models
Predictive Preclinical Models in Oncology
Moscone North Convention Center

San Francisco, CA USA
Predictive Preclinical Models in Oncology
Cambridge Healthtech Institute
Moscone North Convention Center 
San Francisco

Schedule of Presentations:

Monday, February 10, 2014
02:15:00 Session Break
11:50:00 Chairperson’s Opening Remarks
12:00:00 Modeling Efficacy and Resistance of Hedgehog Pathway Inhibitors in Cancer Frederic J. de Sauvage
12:30:00 Bridging Tumor Genomics to Therapeutics through Patient Derived Xenografts (PDXs) David R. Gandara
13:00:00 Session Break
13:15:00 Luncheon Presentation I: The ‘Innovation Universe’ at Oncotest
13:45:00 Luncheon Presentation II (Sponsorship Opportunity Available)
14:30:00 Chairperson’s Remarks
14:35:00 Microenvironmental Regulation of GBM Progression and Therapeutic Resistance Gabrielle Bergers
15:05:00 Resistance to MAPK Pathway Inhibitors in Melanoma: Insights and Future Challenges Jessie Villanueva
15:35:00 PANEL DISCUSSION: Translational Oncology Starts from Predictive Preclinical Models Panelists: Speakers of the Day
16:05:00 Utilization of Predictive Champions TumorGraft Models to Guide Oncology Drug Development
16:35:00 Using Populations of Targeted PDX Models to Support Preclinical Trials of Oncology Therapeutics
16:50:00 Refreshment Break and Transition to Plenary Keynote
17:00:00 Plenary Keynote Session (Click Here For More Details)
18:15:00 Grand Opening Reception in the Exhibit Hall with Poster Viewing
19:45:00 Close of Day
Tuesday, February 11, 2014
05:20:00 Breakout Discussions in the Exhibit Hall
07:00:00 Registration and Morning Coffee
08:00:00 PLENARY KEYNOTE SESSION (Click Here For More Details)
09:15:00 Refreshment Break in the Exhibit Hall with Poster Viewing
10:25:00 Chairperson’s Remarks
10:30:00 Pfizer’s Strategy for the Application of Preclinical Models to Fuel Discovery Biology and Drug Discovery Peter Olson
11:00:00 Biomarker-Guided Breast Cancer Drug Evaluation in I-SPY 2 Laura van ‘ t Veer
11:30:00 Preclinical Models to Help Identify Responder Populations in the Clinic
12:00:00 Found in Translation: Patient-Derived Xenograft Models Define Molecular Signatures of Metastasis and Therapeutic Targets Fredika M. Robertson
12:30:00 Session Break
12:40:00 Luncheon Presentation I: Creating a Functional Human Immune System in Mice to Better
13:10:00 Luncheon Presentation II (Sponsorship Opportunity Available)
13:40:00 Refreshment Break in the Exhibit Hall with Poster Viewing
14:15:00 Chairperson’s Remarks Serguei Kozlov
14:20:00 PREDECT in Europe: Goals and Outcomes ralph graeser
14:50:00 Increasing Predictability of Tumor Animal Models via Systematic Validation Terry Van Dyke
15:20:00 Preclinical and Clinical Applications of Patient Derived Xenograft (PDX) Models
15:50:00 PANEL DISCUSSION: Challenging Cancer Heterogeneity with Reproducible and Predictive Preclinical Studies Terry A. Van Dyke
16:20:00 Valentine’s Day Celebration in the Exhibit Hall with Poster Viewing
18:30:00 Close of Day
Wednesday, February 12, 2014
07:00:00 Breakfast Presentation (Sponsorship Opportunity Available) or Morning Coffee
08:00:00 Plenary Keynote Session (Click Here For More Details)
09:45:00 Refreshment Break and Poster Competition Winner Announced in the Exhibit Hall
10:35:00 Chairperson’s Remarks Tom Metcalfe
10:40:00 Targeting Cancer with BiTE™ Molecules Holger Wesche
11:10:00 Molecular Analysis of Mouse Syngeneic Tumor Models as a Translational Tool in Understanding Anti-PD1 Immunotherapy
11:40:00 Missing The Targets: Why In Vivo Models Are Not Up To The Job Bent Jakobsen
12:10:00 Session Break
12:20:00 Luncheon Presentation (Sponsorship Opportunity Available) or Lunch on Your Own
13:00:00 Refreshment Break in the Exhibit Hall and Last Chance for Poster Viewing
13:40:00 Chairperson’s Remarks
13:45:00 Modeling Tumor Heterogeneity: Accounting for CSCs and the Immune System Elaine Hurt
14:15:00 Integration of Cell Line Sensitivity and Genomic Profiling Data for Patient Stratification
14:45:00 Paradoxical Acceleration of Pancreatic Tumorigenesis through Smoothened Inhibition: A Post-Clinical Trial in Genetically Engineered Mice Kenneth Olive
15:15:00 Sponsored Presentations (Opportunities Available)
15:45:00 Refreshment Break
16:00:00 Chairperson’s Remarks
16:05:00 Development of a Clinically Relevant Model of Metastatic Colorectal Cancer Kevin G. Leong
16:35:00 Impact of Aging and Body Fat on Outcome in Preclinical Cancer Models William J. Murphy
17:05:00 Increasing the Breadth and the Bandwidth of Preclinical Assessment in Biologically Engineered Murine Cancer Models Serguei Kozlov
17:35:00 Close of Conference Program
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