21st Annual Boston Atrial Fibrillation Symposium 2016 (BAFS 2016)
Hyatt Regency Orlando
9801 International Dr, Orlando, FL 32819, United States
Orlando, FL
 The 20th Annual International Atrial Fibrillation Symposium in January 2015 was a great success. We are grateful to all the faculty and attendees who made the meeting such a rich and exciting exchange of new data and ideas for future research.

With the 2015 meeting barely behind us, we have already begun to lay the foundation for 2016 at our new location at the Hyatt Regency Hotel in Orlando, FL. In the coming weeks please check back to review our monthly newsletters, video presentations and updates on this and next year’s meetings.

Twenty First International AF Symposium 2016 Hyatt Regency Hotel, Orlando, FL


It is with great pleasure that I invite you to attend the 21st Annual International AF Symposium on January 14-16, 2016 at the Hyatt Regency Orlando in Orlando, Florida. The Boston AF Symposium was initiated in 1995 in response to the growing epidemic of atrial fibrillation. Over the past 21 years, this meeting has become a major scientific forum at which health-care professionals have a unique opportunity to learn about advances in research and therapeutics directly from many of the most eminent investigators in the field.

This intensive and highly focused three-day symposium brings together the world’s leading medical scientists to share in a highly interactive environment the most recent advances in the field of atrial fibrillation. The primary objective of the meeting is to provide attendees with a thorough and practical view of the current state of the art in the field of AF in a scholarly and collegial atmosphere. The meeting employs advanced teaching tools including satellite and prerecorded case presentations and interactive audience-response systems to share with attendees the most current basic, translational and clinical science in the field.

The past two decades have witnessed dramatic advances in all areas of AF research, which have contributed to major progress in our understanding of the pathophysiology of this arrhythmia and to the development of safer and more effective strategies for the management of AF and the prevention of AF-related stroke. The AF Symposium is dedicated to bringing these advances to our attendees each year in a highly organized and exciting scientific program. 


In 2014, after 18 years in Boston, the meeting was moved to Orlando, Florida, where we were pleased to offer our attendees, industry partners and faculty the opportunity to be housed in one facility. Located just 15 minutes from Orlando International Airport, The Hyatt Regency Orlando offers 1,641 guestrooms, four on-site restaurants, 105 meeting rooms and 315,000 square feet of state-of-the-art flexible function space including five pillar-free ballrooms, a dedicated convention concierge staff, a full service business center, and world-class exercise and recreational facilities onsite. In 2016, the AF Symposium again looks forward to offering attendees and exhibitors easy and comfortable access to the symposium, housing, and a wide range of amenities, all within a single convention facility. We hope that you will join us for the 2016 meeting.

Schedule of Presentations:

Wednesday, January 13, 2016
Thursday, January 14, 2016
06:00:00 Continental Breakfast
06:55:00 Morning Scientific Session
07:00:00 All Lectures are 15 Minutes & 5 Minutes Q&A unless otherwise specified
07:05:00 Welcome and Overview of the 21st Annual AF Symposium Jeremy Ruskin
07:10:00 New Insights into the Pathophysiology, Genetics and Epidemiology of AF Jose Jalife
07:15:00 Ionic Mechanisms in Atrial Arrhythmogenesis Stanley Nattel
07:20:00 Atrial Metabolic Dysfunction as Mechanism and Target in AF Stanley Nattel
07:25:00 Cardiac Autonomic Control: Implications for Understanding AF Mechanisms Kalyanam Shivkumar
07:30:00 Upstream Antifibrotic Therapy Alone is Insufficient to Prevent AF Perpetuation Jose Jalife
07:35:00 Genetics of Atrial Fibrillation: From Discovery to Therapeutic Targeting Patrick Ellinor
07:40:00 Natural History of Atrial Fibrillation and Attributable Morbidity in the Community Steven Lubitz
09:00:00 EXHIBIT FLOOR: Opens
09:10:00 Break and Exhibits
09:40:00 Frontiers in Atrial Fibrillation John Camm
09:45:00 The Fourth Pillar of AF Management – Modifiable Risk Factors: Hypertension, Obesity, Sleep Apnea, Exercise and Stress Reduction – Impact on Outcomes and Success of AF Ablation Hugh Calkins
09:50:00 Long-Term Monitoring with ILRs: Impact on Management of Patients with AF Suneet Mittal
09:55:00 Population Screening for Atrial Fibrillation: Where Do We Stand in 2016? John Camm
10:40:00 Challenging Cases in AF Management: Antiarrhythmic Drugs, Anticoagulation, and Clinical Decision Making Eric Prystowsky, Hans Kottkamp, Peter Kowey, Jeremy Ruskin, Miguel Valderrabano
12:00:00 Lunch and Exhibits
13:30:00 Afternoon Scientific Session | All Lectures are 15 Minutes & 5 Minutes Q&A unless otherwise specified
13:35:00 Clinical Trials and Regulatory Issues in AF Ablation Douglas Packer
13:40:00 CABANA at the End of Enrollment: 2016 Update Douglas Packer
13:45:00 Clinical Trials on New Technologies for AF Ablation Hugh Calkins
13:50:00 FDA Initiatives to Promote Innovation in AF Ablation and Improve New Device Availability (10 minutes) Mark Fellman
13:55:00 FDA Perspective on the Evaluation of Novel Mapping Technologies (10 minutes) Jun Dong
14:00:00 Device Innovation in Arrhythmia Therapy: Challenges to Starting a Medical Device Company Paul Wang
14:10:00 Faculty and Audience Discussion (30 minutes)
14:15:00 What is the Impact of the Current AF Guidelines?
14:20:00 What are Appropriate Endpoints for Clinical Trials on AF?
14:30:00 Audience Q&A
15:10:00 Break and Exhibits
15:40:00 Left Atrial Appendage Closure: Devices, Techniques and Clinical Outcomes Dhanunjaya Lakkireddy
15:45:00 Endocardial, Epicardial and Surgical LAA Closure: Devices and Techniques Dhanunjaya Lakkireddy
15:50:00 New Clinical Outcome Data from LAA Closure Device Trials Vivek Y. Reddy
15:55:00 LAA Closure or Isolation as Adjunctive Therapy to Catheter Ablation for AF Luigi Di Biase
16:00:00 Anticoagulation Management Peri-LAA Closure Including Patients with Major Bleeding Andrea Natale
16:05:00 LAA Closure in Patients with Contraindications to Anticoagulation Bradley Knight
16:10:00 Regulatory Perspectives on Clinical Trials of Left Atrial Appendage Closure Devices Andrew Farb
16:15:00 Lightning Round Panel and Faculty & Audience Discussion (40 minutes) Dhanunjaya Lakkireddy
16:20:00 Is There Consensus on Patient Selection for LAA Closure? Incomplete LAA Closure: Incidence, Significance & Management Economics of LAA Closure: Cost Effectiveness and Reimbursement
16:30:00 Audience Q&A
18:00:00 Adjourn
Friday, January 15, 2016
06:00:00 Continental Breakfast
06:55:00 Morning Scientific Session
07:00:00 All Lectures are 15 Minutes & 5 Minutes Q&A unless otherwise specified
07:00:00 Case Presentations: Catheter Ablation for Atrial Fibrillation Moussa Mansour, Jeremy Ruskin
07:10:00 Catheter Ablation for Persistent Atrial Fibrillation Hikmat Al-Ahmadie, J. David Burkhardt
07:15:00 Catheter Ablation for Longstanding Persistent Atrial Fibrillation Isabel Deisenhofer
07:20:00 Trigger Ablation for Persistent Atrial Fibrillation David Frankel
07:25:00 Catheter Ablation for Atrial Fibrillation Young-Hoon Kim
07:30:00 Catheter Ablation for Atrial Fibrillation Kevin Heist
10:30:00 Break and Exhibits
11:00:00 Optimizing the Safety and Effectiveness of Pulmonary Vein Isolation Part I David Wilber
11:05:00 Update on Balloon Technologies for AF Ablation
11:10:00 Force Sensing During AF Ablation: Impact on Clinical Outcomes Moussa Mansour
11:15:00 Balloon Technologies vs. New Generation RF Ablation Systems Hiroshi Nakagawa
11:20:00 Atrial Lesions with Cryo vs. RF: Short and Long Term Lesion Visualization Study Nassir F. Marrouche
11:25:00 How to Avoid the 5 Biggest Complications of AF Ablation John Day
12:40:00 Optimizing the Safety and Effectiveness of Pulmonary Vein Isolation Part II Francis Marchlinski, John Day, David Keane, Moussa Mansour
12:45:00 Is Routine Use of a Multi-Electrode Circular Mapping Catheter Necessary for Wide Area PV Antral Isolation? Does Routine Pre-Procedural TEE in Low Risk or Anticoagulated Patients Increase Risk for Esophageal Injury Without Added Benefit? Is Routine Use of Esophageal Temperature Probes Safe and Effective in Reducing Risk for Esophageal Injury? Protecting the Esophagus During AF Ablation: What Should We Be Doing in 2016?
13:20:00 Lunch and Exhibits
13:25:00 Afternoon Scientific Session
14:40:00 All Lectures are 15 Minutes & 5 Minutes Q&A unless otherwise specified
14:45:00 Anticoagulation Part I: A New Era in Pharmacological Stroke Prevention in Atrial Fibrillation Daniel Singer
14:50:00 Welcome and Introduction to Anticoagulation Symposium Jeremy Ruskin
14:55:00 Overview of NOACs: Differences in Pharmacology, Drug Interactions and Gaps in Knowledge About Safety and Efficacy Jeffrey I. Weitz
15:00:00 Use of Anticoagulants for AF in Special Situations: Low Risk Score; Peri-Procedural: Ablation, Device Implantation, Cardioversion; Recent Bleeding Peter Kowey
15:05:00 Current Approaches to Double and Triple Antithrombotic Therapy in Patients with AF and PCI (Bare Metal and Drug Eluting Stents) Christopher Granger
15:10:00 Current Status of Reversal Agents for Direct Oral Anticoagulants Jeffrey Weitz
16:00:00 Break and Exhibits
16:30:00 Anticoagulation Part I: A New Era In Pharmacological Stroke Prevention in Atrial Fibrillation (continued) Daniel Singer
16:35:00 Atrial and Ventricular Myopathy: A Novel Risk Predictor for Stroke and Cardiovascular Events Nassir F. Marrouche
16:40:00 Implanted Cardiac Device-Detected AF: Stroke Risk and Indications for Anticoagulation Daniel Singer
16:45:00 Perioperative Management of Anticoagulation in Patients with AF: Recommendations for Clinical Practice Elaine Hylek
17:30:00 Adjourn
Saturday, January 16, 2016
06:00:00 Continental Breakfast
06:55:00 Advances in Catheter Ablation for Persistent AF: Mechanisms, New Tools and Outcomes Douglas Packer
07:00:00 Morning Scientific Session | All Lectures are 15 Minutes & 5 Minutes Q&A unless otherwise specified
07:05:00 Prevalence and Distribution of Non PV Focal Triggers in Persistent AF: Location, Identification and Effect of AF Duration and Gender Francis Marchlinski
07:15:00 Balloon Ablation for Persistent AF: Promise, Limitations, and Next Steps Vivek Y. Reddy
07:20:00 Relationship of AF Termination and Changes in AF Cycle Length to Long Term Outcomes in Catheter Ablation for Persistent AF Atul Verma
07:30:00 Predictors of Clinical Outcomes in Ablation of Persistent AF Drivers Michel Haissaguerre
07:40:00 PVI Plus Box-Isolation of Fibrotic Areas (BIFA) for Persistent AF Hans Kottkamp
07:50:00 AF Ablation in Patients with Persistent AF and Congestive Heart Failure: Benefit Beyond Symptom Relief Andrea Natale
08:00:00 High Resolution Mapping of Atrial Arrhythmias: Impact of Electrode Size and Spacing on Defining Atrial Substrate and Arrhythmia Mechanisms Elad Anter
08:10:00 Panel Discussion: How I Approach Initial and Repeat Ablation Procedures for Persistent AF Audience Q&A Douglas Packer
09:30:00 Break and Exhibits
10:00:00 Rotors and Other Mechanisms in Persistent AF: Concepts and Controversies Jeremy Ruskin
10:05:00 Rotors and Their Substrate in AF: From Experimental Models to Observations in Patients Jose Jalife
10:10:00 The ‘Double-Layer’ Hypothesis: Alternative Explanation for Longstanding Persistent AF in Humans Maurits Allessie
10:15:00 Rotors in Human Atrial Fibrillation – Fact or Fiction Shih-Ann Chen
10:20:00 Mechanisms of Rotor Formation and Elimination in Atrial Fibrillation Sanjiv Narayan
10:25:00 Clinical Outcomes of Rotor Ablation in Multicenter Studies
10:30:00 Monitoring of AF Drivers During Catheter Ablation for Persistent AF Michel Haissaguerre
10:35:00 Intra-Procedural Rotor Mapping and Evolving Approaches to Rotor Ablation in Persistent AF
10:40:00 Impact of Atrial Fibrosis on Rotor Frequency and Location: Evidence from Combined Imaging and Mapping Studies David Wilber
10:45:00 Simultaneous Bi-Atrial High Density Epicardial Mapping – Mechanistic Insights in Patients with Persistent AF: A New Paradigm Albert Waldo
10:50:00 Panel Discussion and Audience Q&A (45 Minutes) Jeremy Ruskin
13:00:00 Lunch and Exhibits
13:55:00 Afternoon Scientific Session
14:00:00 Challenging Cases in Catheter Ablation and LAA Closure for AF David Keane, Moussa Mansour, Andrea Natale, Douglas Packer, Vivek Y. Reddy, David Wilber
15:40:00 Adjourn
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