Ion Channels as therapeutic targets
World Trade Center
200 Seaport Boulevard
Boston, MA

Schedule of Presentations:

Tuesday, October 21, 2008
07:00:00 Registration Open
07:30:00 Morning Coffee
08:30:00 Ion Channels as Therapeutic Targets: Minireview & Chairperson’s Remarks
09:00:00 Ion Channels as Therapeutic Targets to Modulate Cell Proliferation KEYNOTE PRESENTATIONS George Chandy
09:35:00 Improving Ion Channel Lead Generation Capabilities by a Multi-Disciplinary Approach Michael Dabrowski
10:10:00 Grand Opening Coffee Break in the Exhibit Hall
10:40:00 Effective Screening Strategies to Expand the Pharmacology of Ion Channels and Pave the Way for the Next Generation of Ion Channel Therapeutics Laszlo Kiss
11:10:00 in-vitro and in-vivo Pharmacology of Novel TRPV1 Antagonists Anindya Bhattacharya
11:40:00 Progressing at an Accelerated Pace in Ion Channel Drug Discovery—Meeting the Top Two Challenges: PANEL DISCUSSION Anindya Bhattacharya, George Chandy, Michael Dabrowski
12:00:00 New Presentation
12:00:00 New Presentation
12:10:00 High-Throughput Profiling of Ion Channels in Primary Human Cells Michael Mayer
12:40:00 Luncheon Technology Workshop or Lunch on Your Own
13:40:00 Session Break
14:20:00 Chairperson’s Remarks Michael Mayer
14:25:00 Antagonism of the TRPV1 Channel and Thermoregulation Nuria Tamayo
14:55:00 Discovering Small Molecule CRAC Channel Inhibitors Ken Stauderman
15:25:00 Technology Watch
15:55:00 Networking Refreshment Break in the Exhibit Hall
16:30:00 Sodium Channel Drug Discovery in the Era of Automated High-Throughput Electrophysiology Neil A. Castle
17:00:00 Peripheral Nerve Sodium Channels as Analgesic Targets Birgit T. Priest
17:30:00 Sodium Channel Blockers and Pain Mechanisms Jesus Tito Gonzalez
18:00:00 Happy Hour in the Exhibit Hall
19:30:00 End of Day
Wednesday, October 22, 2008
07:30:00 Correlating in vitro Potency with in vivo Efficacy for Ion Channel Modulators, Primary Cell Lines and Automated Patch Clamp Systems for Screening, Outside the Box: Are There Non-Conventional Ways for Ion Channel-Based Drug Discovery? Continental Breakfast Breakout Discussion Sessions Dinah Misner, Chuan-Chu Chou
08:30:00 Chairperson’s Remarks Chuan-Chu Chou
08:40:00 Strategies to Predict QT Prolongation and Arrhythmias: Assessing hERG and Other Cardiac Ion Channels Early in Drug Development Dinah Misner
09:10:00 Addressing the Challenges in Recombinant Expression for Higher Throughput Screens of Ion Channels with Cardiac Liability
09:40:00 Networking Coffee Break in the Exhibit Hall
10:35:00 Chairperson’s Remarks Chuan-Chu Chou
11:10:00 Functional Modulation of AMPA Receptors by Auxiliary Subunits, TARPs Roland Kozlowski
11:40:00 Regulation of Glucose Metabolism by the Voltage-Gated Potassium Channel Kv1.3 and the Intracellular Calcium Sensor Synaptotagmin-7 Gary Desir
12:00:00 New Presentation
12:10:00 Kv1.3 Channels as Targets for Genetic-Induced Obesity and Intranasal Insulin Delivery
12:40:00 Close of Ion Channels Conference
3D Tissue Models
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