Advances in Research Conference: Human Disorders of Protein Processing: Mechanisms, Consequences, and Therapeutic Implications
American Society of Nephrology
1725 I Street, NW Suite 510, 20006
Washington, DC

Schedule of Presentations:

Tuesday, November 4, 2008
07:00:00 Registration and Continental Breakfast
08:00:00 Opening Remarks William R Skach, David H Ellison
08:10:00 Stress Responses and Chaperone Networks in Proteotoxic Stress, Disease, and Aging Richard Morimoto,
09:00:00 Cellular Machinery of Protein Folding F Ulrich Hartl
09:30:00 Hsp70:J-Proteins: Versatile Molecular Chaperone Machines Elizabeth Craig
10:00:00 Break
10:30:00 Biophysics of Protein Folding Lila Gierasch
11:00:00 Cellular Consequences of Protein Misfolding Ron R Kopito
11:30:00 Antitrypsin Deficiency and the Serpinopathies David Lomas
12:00:00 Lunch (provided by ASN)
13:15:00 Protein Lipid Interactions James U Bowie
13:45:00 Vignettes Regarding Membrane Protein Folding and Stability, Misfolding, Disease, and Potential Therapeutics C Sanders
14:15:00 Peptide Insertion and Folding in Membranes Donald Engelman
14:45:00 Break
15:15:00 Folding and Assembly of Mammalian Aquaporins William R Skach
15:45:00 SUR Regulation of KATP Channels Show Ling Shyng
16:15:00 Pharmacological Correction of Nephrogenic Diabetes Insipidus Peter M.T. Deen,
16:45:00 Folding and Misfolding of CFTR deltaF 508 Philip J Thomas
Wednesday, November 5, 2008
07:30:00 Continental Breakfast
08:00:00 The Chaperone-Mediated Selection and Retro-Translocation of Membrane Proteins During ER Associated Degradation (ERAD) Jeffrey L Brodsky
08:30:00 Role of Glycans in ER Quality Control Dan N Hebert
09:00:00 Arginine-based ER Sorting Motifs Blanche Schwappach
09:30:00 Modulation of Proteasome Activity by Stress Daniel Finley
10:00:00 Break
10:30:00 Overcoming ER Quality Control Checkpoints in Cystic Fibrosis Douglas M Cyr
11:00:00 Strategies for Correcting Misfolded PgP
11:30:00 Pharmacological Manipulation of ER Proteostasis Jeffery Kelly
12:10:00 Lunch (On Your Own)
13:15:00 Intracellular Vesicle Transport
13:45:00 Mechanisms of Apical Protein Trafficking Ora A Weisz
14:15:00 Role of Phosphoinositides in Trafficking from the Golgi Peter Mayinger
14:45:00 Break
15:15:00 Golgi Arrest in Inherited K Channelopathies Paul A. Welling
15:45:00 Regulation of Membrane Traffic by OCRL Martin Lowe
16:15:00 Translating Science to Practice: Treatment of Renal Amyloid Laura M. Dember
17:05:00 Closing Remarks David H Ellison, William R Skach
17:20:00 Networking Reception
3D Tissue Models
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