Antibody Engineering
Sheraton San Diego Hotel & Marina

San Diego , CA

Schedule of Presentations:

Sunday, December 7, 2008
12:00:00 Pre-Conference Workshop : Registration Opens
13:30:00 Announcements and Chairperson's Opening Remarks Jamie K Scott
13:45:00 A New Generation of Nanostructures for SPR Biosensing and Antibody Research Alexandre G Brolo
14:15:00 Detection of Cellular and Chemical Activity in Nanoliter Volumes Franz Josef Baudenbacher
14:45:00 Molecular Interaction Studies using Backscattering Interferometry Darryl J Bornhop
15:15:00 Networking Refreshment Break
15:45:00 A Blue-Luminescent Antibody: Mechanism and Applications Erik W Debler
16:15:00 Microwell Arrays for Detecting Single, Antigen-Specific B-lineage Cells Hiroyuki Kishi
16:45:00 Engraved Microarrays for Detecting Single, Antigen-Specific Cells J Christopher Love
17:15:00 Close of Workshop Session; Start of Antibody Society General Session
17:20:00 Special Evening Meeting : The Antibody Society: General Session and Discussion of Specific Initiatives on the Preservation and Advancement of Informatics Resources for the Antibody Engineering Field
Monday, December 8, 2008
07:30:00 Main Conference - Day One : Registration, Networking Coffee
08:00:00 Announcements
08:15:00 Chairperson's Opening Remarks and Keynote Introduction Dennis R Burton
08:30:00 Evolving Technologies of Antibody Engineering
09:30:00 Audience Questions
09:45:00 Networking Refreshment Break
10:15:00 Keynote Introduction by Session Chair
10:30:00 Antibodies: Versatile Proteins for Multiple Applications Sherie Morrison
11:30:00 Audience Questions
11:45:00 Lunch on Your Own
13:15:00 Technology Workshops : Using the ProteOn to Characterize Antigen/Antibody Interactions Yasmina Abdiche
13:15:00 Technology Workshops : Reconstituted Ribosome Display for Efficient Evolution of Antibody Affinity Lutz Jermutus
13:45:00 Technology Workshops : Synthetic Biology and Secretion-Capture Display in Antibody Engineering Dasa Lipovsek
13:45:00 Technology Workshops : A Custom-Designed Approach to Antibody Discovery Linda Masat
14:15:00 Announcements
14:20:00 Session II: The Single-Chain Fv and its Fusion Proteins: 20 Years Old and Coming of Age : Chairperson's Opening Remarks James S Huston
14:30:00 Engineered MFE-23 scFv Fusion Proteins for ADEPT Cancer Therapy and Systems Medicine Richard H.J. Begent
15:00:00 Visualization of Tumor Targeting at High Resolution R. Barbara Pedley
15:30:00 Vascular Targeting with Recombinant Antibody Derivatives: From the Bench to the Clinic Dario Neri
16:00:00 Networking Refreshment Break
16:30:00 Array-Based Oncoproteomics using scFv Microarrays - A Tool for Clinical Diagnostics? Carl A.K. Borrebaeck
17:00:00 Applications of rPEG to dAbs, scFvs and Diabodies Willem 'Pim' Stemmer
17:30:00 scFv Derived by Nanoselection and their Application to Parkinson's Disease and Huntington's Disease Michael Sierks
18:00:00 Networking Cocktail Reception; Opening of Poster and Exhibit Hall
Tuesday, December 9, 2008
07:00:00 Main Conference - Day Two : Registration, Networking Coffee
07:45:00 Announcements
07:50:00 Session III: The Theory, Practice and Use of Libraries Based on Restricted Amino Acid Sets : Chairperson's Opening Remarks Andrew Bradbury
08:00:00 The Antibody Combining Site and Tools to Link Antibody Sequence and Structure Andrew C.R. Martin
08:30:00 Defined-Sequence Libraries in Antibody Engineering Dasa Lipovsek
09:00:00 Slonomics - A Novel Technology for the Generation of Highly Designed Gene Libraries Jan Van den Brulle
09:30:00 Networking Refreshment Break, Exhibit and Poster Viewing
10:15:00 Highly Functional Minimalist Antibodies Sachdev Sidhu
10:45:00 Minimalist Design of Synthetic Binding Proteins using Non-Antibody Scaffolds Shohei Koide
11:15:00 The Path to Platinum: The Evolution of Human Combinatorial Antibody Libraries (HuCAL®) Josef Prassler
11:45:00 Technology Workshops : PER.C6® Cells: A Highly Efficient Production Platform for Antibodies Marco A Cacciuttolo
11:45:00 Technology Workshops : Therapeutic Antibodies without Helper T Cell Epitopes Frank J Carr
12:15:00 Networking Luncheon, Exhibit and Poster Viewing
13:45:00 Technology Workshops : Balancing Power and Simplicity in Real Time, Label-Free Characterization/Selection of Antibodies and Development of Biopharmaceuticals: The Added Value of Biosensors Johan Lindberg
13:45:00 Technology Workshops : Development of MOR103, a GM-CSF Specific Human Antibody for the Treatment of Inflammatory Diseases Currently Tested in a Phase I Clinical Trial Stefan Steidl
13:45:00 Technology Workshops : A Combination of Gene Evolution Technologies for Protein Improvement Christian Kranz
14:15:00 Session IV: Are Non-Antibody Scaffolds Really any Better than Antibody Fragments? : Announcements and Chairperson's Opening Remarks Ian M Tomlinson
14:30:00 Immunogenicity Problems: A Paradigm Shift? Anne S. De Groot
15:00:00 DARPins, the Next Generation Protein Drugs Christian Zahnd
15:30:00 Single Variable Antibody Domains from Camelids - Pros and Cons of Being Camelid Serge Muyldermans
16:00:00 Networking Refreshment Break, Exhibit and Poster Viewing
16:45:00 Human Domain Antibodies: From Selection to Innovative Products Laurent S Jespers
17:15:00 Anticalins®, a Novel Class of Binding Proteins, and their use as Therapeutics Evert J. J. Kueppers
17:45:00 Adnectins: Realizing the Promise of a Novel Class of Targeted Biologics Eric Furfine
18:15:00 Networking Cocktail Reception, Exhibit and Poster Viewing
Wednesday, December 10, 2008
07:30:00 Main Conference - Day Three : Registration, Networking Coffee
08:00:00 Session V: Intrabodies Revisited : Announcements and Chairperson's Opening Remarks Andreas Plückthun
08:15:00 Interfering with RAS-Effector Protein Interactions Inside Cells Terence H Rabbitts
08:45:00 Protein Silencing: Engineering Intrabodies for Targeted Protein Degradation Antonino Cattaneo
09:15:00 Facts and Fairy Tales about Tat-Mediated Uptake of Peptides, Proteins and Antibodies Eric Vives
09:45:00 Networking Refreshment Break, Exhibit and Poster Viewing
10:30:00 Small Molecule Mimics of an Alpha-Helix for Efficient Transport of Proteins into Cells David L Selwood
11:00:00 The Human TOPONOME Project: Translating the Cellular Protein Network Code into Efficient Therapies Walter Schubert
11:30:00 DARPins Inside Andreas Plückthun
12:00:00 Technology Workshops : The ADLib® System: The Most Flexible Technology with Alternative Diversity Hidetaka Seo
12:00:00 Technology Workshops : Clinical Trials Using Potelligent® Mabs Masamichi Koike
12:30:00 Networking Luncheon; Last Chance for Exhibit and Poster Viewing
14:00:00 Session VI: Novel Antibody Targets and Applications : Announcements and Chairperson's Opening Remarks Dennis R Burton
14:15:00 Bacterial Quorum Sensing as a Target for Anti-Infective immunopharmacotherapy Kim D Janda
14:45:00 Molecular Mechanisms of the Anti-Inflammatory Activity Of IVIG Jeffrey Ravetch
15:15:00 New Approaches to Discovery of Effective Prophylactic and Therapeutic Antibodies to Influenza, Including Avian Viruses Jaap Goudsmit
15:45:00 Networking Refreshment Break
16:15:00 Neutralizing Antibody Solutions from H5N1 Avian Influenza Survivor Combinatorial Antibody Libraries Ramesh R Bhatt
16:45:00 Domain Exchanged Antibodies to Glycans Anthony Williamson
17:15:00 A Unique Class of Protective Human Anti-M2 mAbs for Pandemic Influenza Matthew Moyle
17:45:00 Close of Session
Thursday, December 11, 2008
07:30:00 Main Conference - Day Four : Networking Coffee
08:05:00 Session VII: Antibodies in a Complex Environment: Target Selection in Relation to Efficacy : Announcements and Chairperson's Opening Remarks Richard H.J. Begent
08:15:00 B7-H1 Pathway as a Therapeutic Target of Antibody in Cancer and Autoimmune Diseases Lieping Chen
08:45:00 Blocking Inhibitory Self-Recognition to Promote ADCC Louis M Weiner
09:15:00 Systems Optimization of ErbB-Targeted Therapeutics: Development of an Anti-ErbB3 Monoclonal Antibody Ulrik B Nielsen
09:45:00 Networking Refreshment Break
10:15:00 Adapting Antibodies According to Target Diversity in Viral Diseases and Cancer Wayne A Marasco
10:45:00 Anti-Human Transferrin Receptor Avidin Fusion Protein: A Molecule Capable of a Two-Pronged Attack Against Malignant Cells through Toxin Delivery and Direct Induction of Apoptosis Manuel L Penichet
11:15:00 An Integrated System for Tumor Detection and Targeted Drug Therapy using ADEPT: Preclinical, Clinical Testing and Mathematical Modeling Duxin Sun
11:45:00 Lunch on Your Own
13:15:00 Announcements
13:20:00 Session VIII: Mechanism of Antibody Action Revisited : Chairperson's Opening Remarks James D Marks
13:30:00 How Antibody Combinations Synergize to Potently Neutralize Botulinum Neurotoxins James D Marks
14:00:00 Antibody Mixture Regresses Tumors by a Novel Mechanism John Haurum
14:30:00 Selection of Anti-CD22 Antibodies Based on Physiology and Epitope Joseph M Tuscano
15:00:00 Networking Refreshment Break
15:15:00 k-ras Mutations and Response to Cetuximab Treatment David J Mauro
15:45:00 Fc- and Fcγ Receptor-Dependent Mechanisms in Cell-Targeted Monoclonal Antibody Immunotherapy Ezio Bonvini
16:15:00 Enhancement of Effector Function for Small Modular ImmmunoPharmaceutical (SMIP™) Compounds and Other Protein Therapeutics Kendall M. Mohler
16:45:00 Close of Meeting
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