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Peer Reviewed Papers, Books, Chapters

Year Title Citation Authors Review type Summary Keywords File filename File mime type
1. 2002 Formation of Isomorphic Ir3+ and Ir4+ Octamers and Spin Dimerization in the Spinel CuIr2S4 Nature (London), 416, 155 (2002).
2. 1999 Anomalous Melting Transition of the Charge-Ordered State in Manganites Phys. Rev. Lett. 83, 4792 (1999).
3. 1999 Percolative Phase Separation underlies Colossal Magnetoresistance in Mixed-Valent Manganites Nature 399, 560 (1999).
4. 1998 Paired Jahn-Teller Stripes: Basic Building Block in Charge-Ordered (La,Ca)MnO3 Nature 392, 473 (1998).
5. 1998 Paired and Unpaired Charge Stripes in the Ferromagnetic Phase of (La,Ca)MnO3 Phys. Rev. Lett. 81, 3972 (1998).
6. 1997 Impact of Charge Ordering on Magnetic Correlations in Perovskite(Bi,Ca)MnO3 Phys. Rev. Lett. 78, 543 (1997).
7. 1996 Thermodynamic and Electron Diffraction Signatures of Charge and Spin Ordering in La1-xCa xMnO3 Phys. Rev. Lett. 76, 3188 (1996).
8. 1996 The Commensurate to Incommensurate Charge Ordering and Its Real Space Images in La0.5Ca0.5MnO3 Phys. Rev. Lett. 76, 4042 (1996).
9. 1994 Defects in Carbon Nano-Structures Science 263,174 (1994).
10. 1993 Charge Modulations in La2-xSrxNiO4+y: Ordering of Polarons Phys. Rev. Lett. 71, 2461 (1993).
11. Clinical and genetic features incompletely predict outcome in acute myeloid leukemia (AML). Pubmed Clinical and genetic features incompletely predict outcome in acute myeloid leukemia (AML). The value of clinical methylation assays for prognostic markers has not been extensively explored. We assess the prognostic implications of methylC-capture sequencing (MCC-Seq) in patients with de novo AML by integrating DNA methylation and genetic risk stratification. MCC-Seq assessed DNA methylation level in 44 samples. The differentially methylated regions associated with prognostic genetic information were identified. The selected prognostic DNA methylation markers were independently validated in two sets. MCC-Seq exhibited good performance in AML patients. A panel of 12 differentially methylated genes was identified with promoter hyper-differentially methylated regions associated with the outcome. Compared with a low M-value, a high M-value was associated with failure to achieve complete remission (p = 0.024), increased hazard for disease-free survival in the study set (p = 0.039) and poor overall survival in The Cancer Genome Atlas set (p = 0.038). Hematopoietic stem cell transplantation and survival outcomes were not adversely affected by a high M-value (p = 0.271). Our study establishes that MCC-Seq is a stable, reproducible, and cost-effective methylation assay in AML. A 12-gene M-value encompassing epigenetic and genetic prognostic information represented a valid prognostic marker for patients with AML. DNA methylation; MCC-Seq; acute myeloid leukemia; next generation sequencing; prognostic markers


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